Cytochrome-B(5) Reductase

《英文msh詞典》Cytochrome-B(5) Reductase
[主題詞] Cytochrome-B(5) Reductase
[入口詞] Methemoglobin Reductase
[入口詞] NADH Cytochrome B5 Reductase
[入口詞] NADH Methemoglobin Reductase
[入口詞] NADH-Cytochrome B5 Reductase
[入口詞] NADH-Ferrihemoglobin Reductase
[入口詞] B5 Reductase,NADH-Cytochrome
[入口詞] Methemoglobin Reductase,NADH
[入口詞] NADH Ferrihemoglobin Reductase
[入口詞] Reductase,Methemoglobin
[入口詞] Reductase,NADH Methemoglobin
[入口詞] Reductase,NADH-Ferrihemoglobin
[英文釋義] A FLAVOPROTEIN oxidoreductase that occurs both as a soluble enzyme and a membrane-bound enzyme due to ALTERNATIVE SPLICING of a single mRNA. The soluble form is present mainly in ERYTHROCYTES and is involved in the reduction of METHEMOGLOBIN. The membrane-bound form of the enzyme is found primarily in the ENDOPLASMIC RETICULUM and outer mitochondrial membrane,where it participates in the desaturation of FATTY ACIDS; CHOLESTEROL biosynthesis and drug metabolism. A deficiency in the enzyme can result in METHEMOGLOBINEMIA.